Category: Bài báo ngoài nước

Mesenchymal Stem Cells: vector for targeted cancer therapy Binh Thanh Vu, Ngoc Kim Phan, Phuc Van Pham   Abstract Mesenchymal stem cells (MSCs) have been studied extensively due to their potential to differentiate to cell types of varying lineages.Adipose tissue and umbilical cord blood are two tissues frequently used to obtain MSCs. Due to tumor…

What are markers for breast cancer stem cells ? Phuc Van Pham, Nhan Lu-Chinh Phan   Abstract Breast cancer stem cells were firstly discovered by Al-Hajj et al. (2003). Many scientists interested in targeting them as an important solution to “remove” the root of breast cancer. However, more and more publications showed that breast cancer…

Isolation of endothelial progenitor cells from human adipose tissue Phuc Van Pham, Ngoc Bich Vu, Hoa Trong Nguyen, Ngoc Kim Phan   Abstract Adipose tissue is a rich source of stem cells, especially mesenchymal stem cells (MSCs). This study aimed to identify and isolate endothelial progenitor cells (EPCs) from human adipose tissue. Belly adipose tissues…

Concise review: 3D cell culture systems for anticancer drug screening Huyen Thi-Lam Nguyen, Sinh Truong Nguyen, Phuc Van Pham   Abstract Three-dimensional (3D) cultures are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than monolayer cultures. In cancer research, the natural tumor characteristics and architecture are more closely mimicked by…

In vitro and in vivo biocompatibility of Ti-6Al-4V titanium alloy and UHMWPE polymer for total hip replacement Ngoc Bich Vu, Nhung Hai Truong, Long Thanh Dang, Lan Thi Phi, Nga Thi-Thu Ho, Tuan Ngoc Pham, Trinh Phuong Phan, Phuc Van Pham   Abstract Introductions: Joint replacements have considerably improved the quality of life of patients…

A mouse model of osteonecrotic femoral head induced by methylprednisolone and lipopolysaccharide Ha Thi -Ngan Le, Lan Thi Phi, Thuy Thi-Thanh Dao, Ngoc Kim Phan, Phuc Van Pham, Ngoc Bich Vu   Abstract Introduction: Osteonecrosis of the femoral head is caused by various factors, including prolonged use of steroid drugs, use of alcohol, vascular injuries…

Cytokine-induced killer cell transplantation: an innovative adoptive therapy Binh Thanh Vu, Ngoc Kim Phan, Phuc Van Pham   Abstract Cytokine-induced killer (CIK) cells areeffector immune cells with anti-tumor potency of T lymphocytes as well as non-major histocompatibility complex restricted elimination of natural killer cells. Preclinical models have shown that CIK cells have strong anti-tumor killing…

Commentary Open Access Clinical trials for stem cell transplantation: when are they needed? Phuc Van Pham Stem Cell Research & Therapy 2016 7:65 DOI: 10.1186/s13287-016-0325-0 ©  Van Pham. 2016 Published: 27 April 2016 Abstract In recent years, both stem cell research and the clinical application of these promising cells have increased rapidly. About 1000 clinical trials using stem cells…

Abstract            Stem cell therapy is promising for treatment of degenerative diseases. In Vietnam, stem cell applications have been performed since the 1990s. In addition to hematopoietic stem cell transplantation for malignant hematologic diseases and disorders, mesenchymal stem cells have also been clinically approved for treatment of diseases such as knee…

Review Biomedical Research and Therapy February 2016, 3:5 First online: 17 February 2016 Open Access Clinical application of stem cells: An update 2015 Phuc Van Pham Download PDF (2,928 KB) View Article Abstract Stem cell transplantation has the long history of more than 50 years from the first bone marrow transplantation in 1957. From the 2000s, clinical…